This 1926 Pulitzer Prize winning novel centers on the title character, a promising medical student who, as a doctor and following several intervening ventures, becomes a medical researcher in New York. A widespread killer plague takes him to a Caribbean island to produce and inject sera and do research. Fascinating characters, some professional, others romantic, impact his life. Striking similarities of the epidemic in this novel to the pandemic of the 2020's may today seem prophetic. The author won the 1930 Nobel Prize in literature, chiefly for "Arrowsmith".